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Home / Primary Antibodies / Polyclonal Antibodies

GATM antibody

SKU : BHA10803362

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Mfr.No.	FNab03368
Alternative Names	AGAT
Background	This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.
Host	Rabbit
Immunogen	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Isotype	IgG
Molecular Weight	43 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AGAT

Uniprot	P50440
Gene Id	2628
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab03368.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803362	FNab03368	100ug	$240		Add to Cart

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