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Home / Primary Antibodies / Polyclonal Antibodies

GAS2 antibody

SKU : BHA10803344

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Mfr.No.	FNab03350
Background	The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).
Host	Rabbit
Immunogen	growth arrest-specific 2
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	O43903
Gene Id	2620
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab03350.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803344	FNab03350	100ug	$260		Add to Cart

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