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Home / Primary Antibodies / Polyclonal Antibodies

GAD2 antibody

SKU : BHA10803285

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Mfr.No.	FNab03291
Alternative Names	GAD65
Background	This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the production of GABA.
Host	Rabbit
Immunogen	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Isotype	IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	GAD65

Uniprot	Q05329
Gene Id	2572
Research Area	Epigenetics, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IP
Description	ELISA ; WB ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

Manual	FNab03291.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803285	FNab03291	100ug	$240		Add to Cart

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