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Home / Primary Antibodies / Polyclonal Antibodies

GAB2 antibody

SKU : BHA10803266

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Mfr.No.	FNab03272
Alternative Names	KIAA0571
Background	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Host	Rabbit
Immunogen	GRB2-associated binding protein 2
Isotype	IgG
Molecular Weight	70-74 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	KIAA0571

Uniprot	Q9UQC2
Gene Id	9846
Research Area	Developmental biology, Immunology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803266	FNab03272	100ug	$280		Add to Cart

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