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Home / Primary Antibodies / Polyclonal Antibodies

FOXO4 antibody

SKU : BHA10803198

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Mfr.No.	FNab03204
Alternative Names	AFX ; AFX1 ; MLLT7
Background	Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements(IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells(ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Host	Rabbit
Immunogen	forkhead box O4
Isotype	IgG
Molecular Weight	45-48kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AFX, AFX1, MLLT7

Uniprot	P98177
Gene Id	4303
Research Area	Epigenetics, Developmental biology, Signal Transduction, Metabolism, Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803198	FNab03204	100ug	$240		Add to Cart

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