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Home / Primary Antibodies / Polyclonal Antibodies

FMN2 antibody

SKU : BHA10803160

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Mfr.No.	FNab03166
Background	Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis(By similarity). Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis (By similarity). Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress- induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.
Host	Rabbit
Immunogen	formin 2
Isotype	IgG
Molecular Weight	195 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	FMN2, formin 2

Uniprot	Q9NZ56
Gene Id	56776
Research Area	Developmental biology, Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	IHC: 1:50-1:500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803160	FNab03166	100ug	$280		Add to Cart

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