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Home / Primary Antibodies / Polyclonal Antibodies

FLNB antibody

SKU : BHA10803155

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Mfr.No.	FNab03161
Alternative Names	FLN1L ; FLN3 ; TABP ; TAP
Background	This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.
Host	Rabbit
Immunogen	filamin B, beta (actin binding protein 278)
Isotype	IgG
Molecular Weight	298 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	FLN1L, FLN3, TABP, TAP

Uniprot	O75369
Gene Id	2317
Research Area	Developmental biology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:500 - 1:1000; IHC: 1:20 - 1:50

Manual	FNab03161.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803155	FNab03161	100ug	$240		Add to Cart

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