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Home / Primary Antibodies / Polyclonal Antibodies

FKBP8 antibody

SKU : BHA10803143

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Mfr.No.	FNab03149
Alternative Names	FKBP38
Background	Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Host	Rabbit
Immunogen	FK506 binding protein 8, 38kDa
Isotype	IgG
Molecular Weight	53 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	FKBP38

Uniprot	Q14318
Gene Id	23770
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803143	FNab03149	100ug	$280		Add to Cart

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