This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).
Clonality
polyclonal
Host
Rabbit
Immunogen
Fibroblast growth factor 23
Immunogen Region
Fibroblast growth factor 23
Isotype
IgG
Molecular Weight
28 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Synonyms
FGF23, ADHR, FGFN, HPDR2, HYPF, PHPTC
Uniprot
Q9GZV9
Gene Id
8074
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10478.pdf" target="_blank">Data Sheet</ a>