Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Host
Rabbit
Immunogen
FYVE, RhoGEF and PH domain containing 5
Isotype
IgG
Molecular Weight
160 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
FGD5, ZFYVE23
Uniprot
Q6ZNL6
Gene Id
152273
Research Area
Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)