This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
ferritin, light polypeptide
Isotype
IgG
Molecular Weight
18 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
Ferritin L subunit, Ferritin light chain, ferritin, light polypeptide, FTL
Uniprot
P02792
Gene Id
2512
Research Area
Immunology, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)