Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Host
Rabbit
Immunogen
fem-1 homolog b
Isotype
IgG
Molecular Weight
Q9UK73
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
F1A alpha, F1AA, fem 1 homolog b, FEM1 beta, FEM1B, FIAA, KIAA0396, Protein fem 1 homolog B
Uniprot
Q9UK73
Gene Id
10116
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)