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Home / Primary Antibodies / Monoclonal Antibodies

FAS/CD95 antibody

SKU : BHA10803011

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Mfr.No.	FNab03017
Background	Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	Fas(TNF receptor superfamily, member 6)
Isotype	IgG2a
Molecular Weight	38-45 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

Uniprot	P25445
Gene Id	355
Clone No	4B6
Research Area	Cancer, Immunology, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, FC
Description	ELISA ; WB ; FC
Tested Application	WB: 1:1000-1:8000; IHC: 1:50-1:500

Manual	FNab03017.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803011	FNab03017	100ug	$280		Add to Cart

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