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Home / Primary Antibodies / Polyclonal Antibodies

FANCA antibody

SKU : BHA10802997

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Mfr.No.	FNab03003
Alternative Names	FAA ; FACA ; FANCH
Background	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.
Categories	Primary Antibodies
Clonality	polyclonal
Description	DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Host	Rabbit
Immunogen	Fanconi anemia, complementation group A
Isotype	IgG
Molecular Weight	163 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	FAA, FACA, FANCH

Uniprot	O15360
Gene Id	2175
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab03003.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802997	FNab03003	100ug	$280		Add to Cart

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