FAM3C, also known as ILEI, is a secreted protein belonging to the cytokine-like protein family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. A change in expression of this protein has been noted in pancreatic cancer-derived cells. FAM3C has been involved in the epithelial to mesenchymal transition, and retinal laminar formation processes in vertebrates. Also, FAM3C may play an important role in inner ear development and thus be involved in cell differentiation and proliferation during inner ear embryogenesis.
Categories
Primary Antibodies
Clonality
monoclonal
Description
May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition.
Host
Mouse
Immunogen
family with sequence similarity 3, member C
Isotype
IgG2a
Molecular Weight
25kd
Reactivity
Human
Regulatory
RUO
Synonyms
FAM3C, Protein FAM3C, GS3786, Interleukin like EMT inducer, ILEI
Uniprot
Q92520
Gene Id
10447
Clone No
2A10
Research Area
Cell Division and Proliferation, Signal Transduction
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)