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Home / Primary Antibodies / Polyclonal Antibodies

FADD antibody

SKU : BHA10802935

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Mfr.No.	FNab02941
Alternative Names	MORT1
Background	Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Host	Rabbit
Immunogen	Fas(TNFRSF6)-associated via death domain
Isotype	IgG
Molecular Weight	26 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	FADD, GIG3, MORT1, Protein FADD

Uniprot	Q13158
Gene Id	8772
Research Area	Immunology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, IP
Description	ELISA ; IHC ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200

Reference	Journal: The International Journal of Biochemistry & Cell Biology Title: Edaravone Attenuates Neuronal Apoptosis in Hypoxic-Ischemic Brain Damage Rat Model via Suppression of TRAIL Signaling Pathway

Manual	FNab02941.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802935	FNab02941	100ug	$240		Add to Cart

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