This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.
Categories
Primary Antibodies
Clonality
polyclonal
Description
High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
Host
Rabbit
Immunogen
fatty acid binding protein 5 (psoriasis-associated)
Isotype
IgG
Molecular Weight
15 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
Q01469
Gene Id
2171
Research Area
Developmental biology, Cardiovascular, Metabolism, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)