The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.
Categories
Primary Antibodies
Clonality
polyclonal
Description
FABP3 (fatty-acid-binding protein 3), also known as heart-type FABP or mammary-derived growth inhibitor (MDGI), is a small 15-kDa cytoplasmic protein transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus. It is most ubiquitously expressed in heart and skeletal muscle.
Host
Rabbit
Immunogen
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Isotype
IgG
Molecular Weight
14 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
FABP11, FABP3, Fatty acid binding protein 3, H FABP, HFABP, M FABP, MDGI, O FABP
Uniprot
P05413
Gene Id
2170
Research Area
Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Cancer, Stem Cells
Weight
15kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)