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Home / Primary Antibodies / Polyclonal Antibodies

EXD1 antibody

SKU : BHA10802883

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Mfr.No.	FNab02889
Alternative Names	EXDL1
Background	RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing- triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease (By similarity).
Host	Rabbit
Immunogen	exonuclease 3'-5' domain containing 1
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	EXDL1

Uniprot	Q8NHP7
Gene Id	161829
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802883	FNab02889	100ug	$240		Add to Cart

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