Directs the termination of nascent peptide synthesis(translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Host
Rabbit
Immunogen
eukaryotic translation termination factor 1
Isotype
IgG
Molecular Weight
45-48kd
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
ERF1, RF1, SUP45L1
Uniprot
P62495
Gene Id
2107
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)