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Home / Primary Antibodies / Polyclonal Antibodies

ERK1/2 antibody

SKU : BHA10802838

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Mfr.No.	FNab02844
Alternative Names	ERK ; ERK1 ; ERK1 ; ERK1/2 ; ERT2 ; HS44KDAP ; HUMKER1A ; InsulinstimulatedMAP2kinase ; MAPkinase3 ; MAPkinaseisoformp44 ; MAPK3
Background	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Ucleus
Clonality	polyclonal
Description	ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF. This antibody can recognize both ERK1 and ERK2.
Host	Rabbit
Immunogen	mitogen-activated protein kinase 3
Isotype	IgG
Molecular Weight	40 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm,Nucleus
Synonyms	ERK, ERK 1, ERK1, ERK1/2, ERT2, HS44KDAP, HUMKER1A, Insulin stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44, MAPK 3, MAPK3, p44 ERK1, p44 MAPK, P44ERK1, P44MAPK, PRKM3

Uniprot	P27361
Gene Id	5595
Research Area	Cell Division and Proliferation, Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience
Weight	44kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

IHC	1:20-1:200
IF	1:10-1:100

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02844.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802838	FNab02844	100ug	$260		Add to Cart

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