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Home / Primary Antibodies / Polyclonal Antibodies

ERCC3 antibody

SKU : BHA10802828

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Mfr.No.	FNab02834
Alternative Names	XPB ; XPBC
Background	This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
Categories	Primary Antibodies
Clonality	polyclonal
Description	ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.
Host	Rabbit
Immunogen	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
Isotype	IgG
Molecular Weight	80 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	XPB, XPBC

Uniprot	P19447
Gene Id	2071
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02834.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802828	FNab02834	100ug	$240		Add to Cart

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