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Home / Primary Antibodies / Polyclonal Antibodies

ERCC2 antibody

SKU : BHA10810721

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Mfr.No.	FNab10932
Background	ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair(NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase(CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Clonality	polyclonal
Host	Rabbit
Immunogen	excision repair cross-complementing rodent repair deficiency, complementation group 2
Immunogen Region	eXcision repair cross-complementing rodent repair deficiency, complementation group 2
Isotype	IgG
Molecular Weight	80 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500-1:2000
Synonyms	XPD, XPDC

Uniprot	P18074
Gene Id	2068
Research Area	Epigenetics, Cancer, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10932.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810721	FNab10932	100ug	$280		Add to Cart

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