Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Host
Rabbit
Immunogen
endoplasmic reticulum aminopeptidase 2
Isotype
IgG
Molecular Weight
61 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP
Uniprot
Q6P179
Gene Id
64167
Research Area
Cardiovascular, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)