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Home / Primary Antibodies / Polyclonal Antibodies

ER antibody

SKU : BHA10802816

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Mfr.No.	FNab02822
Alternative Names	DKFZp686N23123 ; ER ; ERalpha ; Era ; ESR ; ESR1 ; ESRA ; Estradiolreceptor ; Estrogenreceptor ; estrogenreceptor1 ; NR3A1
Background	This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Categories	Primary Antibodies
Clonality	polyclonal
Description	The estrogen receptor (ESR, ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. ESR1, also known as ESR or NR3A1, belongs to the nuclear hormone receptor family and NR3 subfamily. It is a nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. ESR1 can activate the transcriptional activity of TFF1.
Host	Rabbit
Immunogen	estrogen receptor 1
Isotype	IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	DKFZp686N23123, ER, ER alpha, Era, ESR, ESR1, ESRA, Estradiol receptor, Estrogen receptor, estrogen receptor 1, NR3A1

Uniprot	P03372
Gene Id	2099
Research Area	Developmental biology, Cell Division and Proliferation, Signal Transduction, Metabolism, Immunology, Cancer, Neuroscience
Weight	66kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB

Description

ELISA ; IHC ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200

Manual	FNab02822.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802816	FNab02822	100ug	$240		Add to Cart

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