This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
Clonality
monoclonal
Host
Mouse
Immunogen
Ephrin type-A receptor 2
Immunogen Region
Ephrin type-A receptor 2
Isotype
IgG1
Molecular Weight
130 kDa
Reactivity
Human
Recommended Dilution
WB: 1:2000-1:20000
Synonyms
ARCC2, CTPA, CTPP1, CTRCT6, ECK
Uniprot
P29317
Clone No
2B8
Form
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:2000-1:20000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10497.pdf" target="_blank">Data Sheet</ a>