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Home / Primary Antibodies / Polyclonal Antibodies

EPCAM antibody

SKU : BHA10802793

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Mfr.No.	FNab02799
Alternative Names	GA733-2 ; M1S2 ; M4S1 ; MIC18 ; TACSTD1 ; TROP1
Background	This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. (PMID: 20837599; 19249674; 21576002; 22647938)
Host	Rabbit
Immunogen	epithelial cell adhesion molecule
Isotype	IgG
Molecular Weight	40 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1

Uniprot	P16422
Gene Id	4072
Research Area	Stem Cells, Immunology, Signal Transduction, Cancer
Weight	40kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:200

Manual	FNab02799.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802793	FNab02799	100ug	$260		Add to Cart

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