Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor(GEF) activity of DOCK1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Host
Rabbit
Immunogen
engulfment and cell motility 2
Isotype
IgG
Molecular Weight
83 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CED12A, KIAA1834
Uniprot
Q96JJ3
Gene Id
63916
Research Area
Cancer, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)