This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14.
Clonality
polyclonal
Host
Rabbit
Immunogen
ELK1, member of ETS oncogene family
Immunogen Region
ELK1, member of ETS oncogene family
Isotype
IgG
Molecular Weight
45 kDa
Reactivity
Human, Rat
Recommended Dilution
IHC: 1:20-1:200
Synonyms
ELK1, ELK1, ETS transcription factor
Uniprot
P19419
Gene Id
2002
Research Area
Immunology, Cardiovascular, Metabolism, Signal Transduction
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10070.pdf" target="_blank">Data Sheet</ a>