Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex(40S.mRNA.Met-tRNA(F).eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex(80S.mRNA.Met-tRNA(F)).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
Host
Rabbit
Immunogen
eukaryotic translation initiation factor 5
Isotype
IgG
Molecular Weight
50 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
P55010
Gene Id
1983
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)