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Home / Primary Antibodies / Polyclonal Antibodies

EIF4G1 antibody

SKU : BHA10802718

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Mfr.No.	FNab02724
Alternative Names	EIF4F ; EIF4G ; EIF4GI
Background	The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
Host	Rabbit
Immunogen	eukaryotic translation initiation factor 4 gamma, 1
Isotype	IgG
Molecular Weight	230 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	EIF4F, EIF4G, EIF4GI

Uniprot	Q04637
Gene Id	1981
Research Area	Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab02724.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802718	FNab02724	100ug	$240		Add to Cart

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