This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP.
Host
Rabbit
Immunogen
elongation factor Tu GTP binding domain containing 2
Isotype
IgG
Molecular Weight
120 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0031, SNRP116
Uniprot
Q15029
Gene Id
9343
Research Area
Epigenetics, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)