EAAT2 (also known as GLT-1), is encoded by SLC1A2 and is a glutamate transporter which can clear the majority of extracellular glutamate in brain and prevent brain seizures.Three isoforms of EAAT2 exist due to the alternative splicing. In addition to the 65-70 kDa monomer form, 120-140 kDa dimer of EAAT2 can also be observed on SDS-PAGE. (PMID: 22114258)
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
solute carrier family 1(glial high affinity glutamate transporter), member 2
Isotype
IgG
Molecular Weight
60-70 kDa, 120 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
EAAT2, EIEE41, GLT-1, HBGT
Uniprot
P43004
Gene Id
6506
Research Area
Developmental biology, Signal Transduction, Metabolism, Stem Cells, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)