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Home / Primary Antibodies / Polyclonal Antibodies

E2F4 antibody

SKU : BHA10802596

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Mfr.No.	FNab02602
Background	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC(CG)CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Host	Rabbit
Immunogen	E2F transcription factor 4, p107/p130-binding
Isotype	IgG
Molecular Weight	60-70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q16254
Gene Id	1874
Research Area	Cell Division and Proliferation, Developmental biology, Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802596	FNab02602	100ug	$240		Add to Cart

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