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Home / Primary Antibodies / Polyclonal Antibodies

E2F1 antibody

SKU : BHA10802594

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Mfr.No.	FNab02600
Alternative Names	RBBP3
Background	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC(CG)CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters(PubMed:20176812).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
Host	Rabbit
Immunogen	E2F transcription factor 1
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	RBBP3

Antigen	E2F1
Uniprot	Q01094
Gene Id	1869
Research Area	Cell Division and Proliferation, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802594	FNab02600	100ug	$240		Add to Cart

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