DVL1 is one of three DVL homologous proteins (DVL13) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway.
Clonality
polyclonal
Host
Rabbit
Immunogen
dishevelled, dsh homolog 1
Immunogen Region
dishevelled, dsh homolog 1
Isotype
IgG
Molecular Weight
70 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Synonyms
Dishevelled 1, DSH homolog 1, DVL, DVL1
Uniprot
O14640
Gene Id
1855
Research Area
Developmental biology, Signal Transduction, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:500
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09841.pdf" target="_blank">Data Sheet</ a>