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Home / Primary Antibodies / Polyclonal Antibodies

DTX2 antibody

SKU : BHA10802548

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Mfr.No.	FNab02554
Alternative Names	KIAA1528 ; RNF58
Background	DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Host	Rabbit
Immunogen	deltex homolog 2 (Drosophila)
Isotype	IgG
Molecular Weight	67 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1528, RNF58

Uniprot	Q86UW9
Gene Id	113878
Research Area	Developmental biology, Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02554.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802548	FNab02554	100ug	$260		Add to Cart

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