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Home / Primary Antibodies / Polyclonal Antibodies

DOK1 antibody

SKU : BHA10802494

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Mfr.No.	FNab02500
Background	The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Several transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Host	Rabbit
Immunogen	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Isotype	IgG
Molecular Weight	52 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q99704
Gene Id	1796
Research Area	Immunology, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab02500.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802494	FNab02500	100ug	$280		Add to Cart

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