Increases DNTT terminal deoxynucleotidyltransferase activity(in vitro)(PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5'- GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
Host
Rabbit
Immunogen
deoxynucleotidyltransferase, terminal, interacting protein 1
Isotype
IgG
Molecular Weight
37 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
C20orf167, TDIF1
Uniprot
Q9H147
Gene Id
116092
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)