GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
Categories
Primary Antibodies
Clonality
polyclonal
Description
GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
Host
Rabbit
Immunogen
DnaJ(Hsp40) homolog, subfamily C, member 27
Isotype
IgG
Molecular Weight
31 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
RABJS, RBJ
Uniprot
Q9NZQ0
Gene Id
51277
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)