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Home / Primary Antibodies / Polyclonal Antibodies

DMP1 antibody

SKU : BHA10810453

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Mfr.No.	FNab10499
Background	Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	Dentin matrix acidic phosphoprotein 1
Immunogen Region	Dentin matriX acidic phosphoprotein 1
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Synonyms	DMP1, ARHP, ARHR, DMP-1

Uniprot	Q13316

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10499.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810453	FNab10499	100ug	$280		Add to Cart

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