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Home / Primary Antibodies / Polyclonal Antibodies

DLC1 antibody

SKU : BHA10802399

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Mfr.No.	FNab02405
Alternative Names	ARHGAP7 ; KIAA1723 ; STARD12
Background	This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
Host	Rabbit
Immunogen	deleted in liver cancer 1
Isotype	IgG
Molecular Weight	171 kDa
Reactivity	Mouse, Rat
Regulatory	RUO
Synonyms	ARHGAP7, KIAA1723, STARD12

Uniprot	Q96QB1
Gene Id	10395
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, IF, IP
Description	ELISA ; IHC ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02405.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802399	FNab02405	100ug	$240		Add to Cart

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