This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
Clonality
polyclonal
Host
Rabbit
Immunogen
dicer 1, ribonuclease type III
Immunogen Region
dicer 1, ribonuclease type III
Isotype
IgG
Molecular Weight
90-100 kDa, 210-250 kDa
Reactivity
Human
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
DICER, HERNA, KIAA0928
Uniprot
Q9UPY3
Gene Id
23405
Research Area
Epigenetics, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10456.pdf" target="_blank">Data Sheet</ a>