Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1.
Host
Rabbit
Immunogen
dihydrofolate reductase
Isotype
IgG
Molecular Weight
21 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DHFR, DHFRP1, dihydrofolate reductase
Uniprot
P00374
Gene Id
1719
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)