Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor(GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2(T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
Host
Rabbit
Immunogen
differentially expressed in FDCP 6 homolog(Mouse)
Isotype
IgG
Molecular Weight
74 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
IBP
Uniprot
Q9H4E7
Gene Id
50619
Research Area
Signal Transduction, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)