RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation.
Host
Rabbit
Immunogen
DEAD(Asp-Glu-Ala-Asp) box polypeptide 17
Isotype
IgG
Molecular Weight
72 kDa, 80 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DDX17, DEAD box protein 17, DEAD box protein p72, P72, RH70, RNA dependent helicase p72
Uniprot
Q92841
Gene Id
10521
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)