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Home / Primary Antibodies / Polyclonal Antibodies

DDR1 antibody

SKU : BHA10802285

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Mfr.No.	FNab02291
Alternative Names	CAK ; EDDR1 ; NEP ; NTRK4 ; PTK3A ; RTK6 ; TRKE
Background	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Host	Rabbit
Immunogen	discoidin domain receptor tyrosine kinase 1
Isotype	IgG
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE

Uniprot	Q08345
Gene Id	780
Research Area	Immunology, Cardiovascular, Metabolism, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802285	FNab02291	100ug	$240		Add to Cart

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