Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate(PI(3)P), phosphatidylinositol 4-phosphate(PI(4)P), phosphatidylinositol 5-phosphate(PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate(PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4- phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane.
Host
Rabbit
Immunogen
DDHD domain containing 2
Isotype
IgG
Molecular Weight
80-90 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0725, SAMWD1
Uniprot
O94830
Gene Id
23259
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)