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Home / Primary Antibodies / Polyclonal Antibodies

DAO antibody

SKU : BHA10802229

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Mfr.No.	FNab02235
Alternative Names	DAMOX
Background	This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Host	Rabbit
Immunogen	D-amino-acid oxidase
Isotype	IgG
Molecular Weight	39 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	DAMOX

Uniprot	P14920
Gene Id	1610
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab02235.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802229	FNab02235	100ug	$240		Add to Cart

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