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Home / Primary Antibodies / Polyclonal Antibodies

Cytokeratin 8 antibody

SKU : BHA10802215

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Mfr.No.	FNab02221
Alternative Names	CARD2 ; CK8 ; CK8 ; CYK8 ; Cytokeratin8 ; K2C8 ; K8 ; keratin8 ; KO ; KRT8 ; TypeIIkeratinKb8
Background	This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT8 is often paired with keratin 18 in vivo.
Host	Rabbit
Immunogen	keratin 8
Isotype	IgG
Molecular Weight	53 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	CARD2, CK 8, CK8, CYK8, Cytokeratin 8, K2C8, K8, keratin 8, KO, KRT8, Type II keratin Kb8

Uniprot	P05787
Gene Id	3856
Research Area	Developmental biology, Stem Cells, Immunology, Cancer
Weight	54kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, FC, IF, IHC

Description

ELISA ; WB ; FC ; IF ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:10-1:100

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab02221.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802215	FNab02221	100ug	$240		Add to Cart

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